Posted 24 days ago
HPV is the main cause of oropharyngeal squamous cell carcinoma. CDCs establish that HPV is the most common sexual infection in the United States. Or the more than 100 types of HPV, approximately 40 types can be extended through direct sexual contact to genital areas, as well as mouth and throat. Oral HPV can be transmitted to the mouth by oral sex or other ways.
Many people are exposed to HPV oral in their lives. About 10% of whether one and 3.6% of women have HPV oral, and Oral HPV infection is more common with advanced age. The age of the diagnosis of HPV squamous cell carcinoma begins in men and women at age 30 and reaches its maximum point between 60-69 and then begins to decrease after that. Most people clear HPV in 1 to 2 years, but HPV infection persists in some people.
HPV can infect the mouth and throat. Usually, it has been infected with HPV for years for cancers to develop in the oropharynx. This includes the back of the throat, including the base of the tongue and the tonsils. However, HPV oropharyngeal cancer must cause 60% to 70% of oropharyngeal cans in the United States. It is not known that HPV causes other heads and neck cancers, including those of the larynx, lip, nose or great salivals. Oropharyngeal cancer related to HPV is the eighth most common cancer in men.
There is a difference between oropharyngeal cancer of HPV and the negative cancer of HPV. The negative HPV cancer is generally caused by tobacco and alcohol factors. The positive oropharyngeal cancers of HPV tend to respond more to treatment.
Symptoms include sore throat, ear pains, swollen lymph nodes, swallowing pain and inexplicable weight loss. Some patients have no symptoms.
The general 5 -year survival rate in patients with oropharyngeal cancer is approximately 52%. However, the prognosis for the positive survival rate of HPV is> 80% of negative HPV patients have a survival rate of <50%. With more than 13,000 new throat cancer diagnoses every year in the US, the disease has surpassed cervical cancer as the most common chain with HPV.
A 46 -year -old mino patient presented to the clinic with chronic throat pain. He had bones having problems with him for approximately 2 years and had a sea for an Entypyicista. He had fallen and lowered the stairs recently and a massage therapist observed a lump. He was examined and was fired for having a bruise due to trauma. He had been my patient for many years who arrived regularly for routine dental restoration problems and hygiene quotes. It was presented to the clinic with the back base of the swelling of the tongue, the swelling of the left leaflet, the chronic throat pain, the submandibular swelling and the weight loss. He had felt good for a while. He had recently dropped his primary care doctor who also fired him as a viral. The PCP tested for the streptococcal throat twice, but the results of the two times were negative. The palpation of the left neck region revealed a swollen submandibular lymphatic gland of the size of a room with mobility. The intraoral exam revealed an area of red and swollen pillar pillar on the left side and unusual swelling at the base of the tongue. It was difficult to visualize due to swelling and its gag reflection. Low level laser therapy was applied to the area using an Erbium/yag and yag of light and yag light and yag using both media on a twice weekly base.
He returned two weeks later with continuous discomfort. The patient noticed more swelling in the area of cervical lymph nodes. We continued low -level Laser therapy ND/YAG twice a week for approximately 3 weeks, since the patient declared that things were improving, but still felt some pain in the neck and jaw. A recent CBCT revealed asymmetry on the left side of the lower oropharynx near the epiglottis.
He was immediately sent to the Entrert office for additional evaluation. I sent you to the Ent office a photo of a recent CBCT and an intraoral photo. The doctor’s assistant saw the patient and fired my snapshot of the CBCT and the photo, but touched a biopsy of the left tonsilian pit.
The biopsy returned positive in the HVP HVP squamous cell carcinoma in stadium IV. Due to the scope of carcinoma, surgical intervention was ruled out and a combination of chemotherapy and radiation was instituted to try to reduce carcinoma.
Image 1 – Intraoral photo of the lesion at the base of the tongue
Image 2 and 3 – Transversal and axial view Of CBCT 8 years ago
Image 4 and 5 – Transversal and axial view for 1 year that shows pathology
Sectional and axial view of image 6 and 7 Cross several months after chemotherapy and radiotherapy
The patient seems to be well after treatment. Recently a biopsy was performed that stole the carotid artery and required ligation of the artery to stop bleeding. The biopsy was free of any carcinoma.
In retrospect, the sore throat and continuous swelling should have a red flag followed by its PCP. However, I am slippery, we were able to discover this injury and reference quickly to save the food and trace functions of this gentleman and his life.
John Rothchild, DDs.