Artificial sweets such as Aspartamo have long been marketed as a healthier alternative to sugar, offering the sweetness that people yearn without additional calories. But a new study suggests that aspartamo can come with its own set of risks, specifically, for the health of the heart. Researchers at the Karolinska Institute in Sweden found that Aspartamo consumption significantly increased insulin levels and led to the accumulation of fatty plates in the arteries, a key taxpayer to atherosclerosis and heart disease.
The study, published in Cell metabolismIt raises serious questions about the long -term effects of this widely used sugar substitute.
What did the study find?
The researchers fed mice with a diet containing 0.15% aspartamo for 12 weekly equivalents to a human who drinks three diet soft drinks per day. Compared to a control group, the mice fed with aspartamo showed alarm changes:
- Largest and largest arterial plaque accumulationA key promoter of heart disease.
- Higher levels or inflammationwhich is related to cardiovascular disease.
- A significant peak at insulin levels Shortly after Aspartame Innion.
The study suggests that Aspartamo deceives the sweet taste receptors of the body to trigger insulin release, even thought there was no real sugar to process. This increase in insulin is activated after immune signaling protein on the walls of blood vessels (CX3cl1), which promotes the formation of inflammatory and arterial plaque.
Why does this matter
Atherosclerosis, the accumulation of plates in the arteries, is an important risk factor for heart attacks and strokes. The results indicate that regular consumption of Aspartamo could be a taxpayer overlooked this deadly condition.
Professor Yihai Cao, who directed the research, explained: “CX3CL1 on the walls of the blood vessels acts as a magnet, catching inflammatory immune cells. When we eliminate the CX3cl1 receptor in the mice fed with aspartamo, the accumulation of harmful plaque disappeared.”
This suggests that Insulin can be the missing link between artificial sweets and cardiovascular disease. While adjustment studies have linked artificial sweets with metabolic disorders, the exact mechanism was not clear -tile now.
Aspartamo: harmless or harmful?
The aspartamo has a controversial leg for decades. It is what 200 times sweeter than sugar And it almost does not contain calories, which makes it a popular ingredient in diet sodas, sugar -free rubber and even yogurt. He The FDA considers it saferecommending a daily limit of 50 mg per kilogram or body weight“Halby around.” 19 dietary soda cans for a 70 kg person (154 lb).
However, studies such as this suggest that equally moderate amounts could have unintentional effects on the body, especially for those who are already at risk of heart disease.
What follows?
The study was conducted in mice, then Human essays are needed To confirm that the same effects occur in people. Professor Cao and his team plan to investigate this more thoroughly.
Until then, the debate on artificial sweets continues. While reducing sugar is a good idea for general health, replacing it with artificial alternatives may not be the perfect solution. If you are worried about your heart, it could be worth it that the daily sodas of the diet.
End
This study does not mean that it must prohibit the aspartamo of its diet completely, but highlights the need for caution. As researchers work to understand the total impact of artificial sweets, one thing is clear: when it comes to health, “Without sugar” does not always mean risk -free.
